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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '228f5ab5de73227b61e94c851a425901e659f39a116c3fde6f114eca5e588a72' 
  AND token = 'HsrHnHf1Tku7Uue2EoSvoOw1y4zP10cW4jlYo+48fAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}