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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '286c1bf85ab6eb00a2fb7bc8f481866567eef6ebdfa2b688ff53c8b63b260d49' 
  AND token = '2rStCWsisWFZpgXASxngl7Dg9iwq9iWJ1IYBT0CWMl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}