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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecae749d2c1ad5188a81ca1d1b768e6f33e65134671cdaf7d0ffd42103b8ca66' 
  AND token = '7FkgFvxE932nCcmIQ/+d+b7KJGR2Jn3Qe2H3lpR+Geg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}