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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eff47e32535378821a4f02737fba348ca29afc32572942572d2985aabf009b5' 
  AND token = 'kNM0TAhofl9pQy3VZezp+N4wzCsQ9mWyqnSfH1vK+G0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}