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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '605a60904b9682d52c40d4ccaaa22232d469629616cc0292a5a1762a97a18c22' 
  AND token = 'SIISAtAgRhf5+DTgGZuNwTsIl+1IHPq3FZH7Q9+644Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}