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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18db57cd7e486a5018e2b6f46f278998d55790c0166f941447800cbfa992edc7' 
  AND token = 'Bg8AsQsURKCmLU+eXWtRQ2MhVtFFFG6tzehT+bLT6og=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}