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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb8222876d3ec14aa2cd3b6e0403c27c90af379714a81092a95d433c26522602' 
  AND token = 'p7AznFI1GYdhwUs0GWFjKWaiMZGEEB4AXEtAOK9s1oI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}