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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a0a1705eb832eca3b34d152e926fbc4510e6f55c205977ccfdd856ca69a6182' 
  AND token = 'p+rKJLQz/27H1rSQ3HkbAk0k6elmPp6aliQjK+42otQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}