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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e4ffe65635c54cdad1986f7f846cdf0d1e61f7c2fe3313eea1d6c0424cce7a2' 
  AND token = 'au63VmWXd3sRW+qTgcM5P93KKBH9/jVAUUuUTSWrH7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}