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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aea5a5e82358bec38c03832786e77510641bcce843ff6166cf8c27769a40a3c2' 
  AND token = 'xjfZp3NUwNXcZ+hm45BYYmJl4CPUecS+Qx31KSu8x4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}