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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab8ec40486dfa69012b7f4a9560e0aa31fa40f8403ec874d489cdff425e6a36b' 
  AND token = 'Z0dWzAt6wQNK6XbZcc2y2gq2Kiru1uFpPsM1w5eUGwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}