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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2116a2008cc8f90e6105394320a99460fdb2fc762d46d43896c70b1bb42313b7' 
  AND token = 'TMotl+SO9uPfxg9+xafKtKi3cddeO0cib7e5B7hDKZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}