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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '774e7476a267c5212c417ec1323c5a181ac03496de13c607b4f15841f07a8de0' 
  AND token = '1J3VDRzmr5zyWpeknWxjHYUrL8L9DTnlWhtxlI+lpes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}