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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2731da833b5c5482a2c9136eefd6447205496a44d831e830d91f3d77e950eef3' 
  AND token = '3Ay3GI3hdBpjpVOtmXCHPFdxGKteS4a4j4j8JJ2tjuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}