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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd29bc75b0484635d4349f920fd1dd8e2daaae0d29110ec49c618f2a45d67d68f' 
  AND token = 'K5RpQlhYieFuPhKM6jIJbESTbHkxCCaV1O9W1rEsBI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}