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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4bec7d63018476b36b7a26aef3c88056f8a10a6f75f4947dd8f6ae52031375a' 
  AND token = 'EC+p5RjZmKZAFMr6FyA/K7IYUf7eUpKhrJTG8J37hEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}