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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8066ca2f3e69b357f6413e6a9cd43f1f726460958c02c417dba7ed85f6acc060' 
  AND token = 'KAKPNfgkWBuYHbLQSlL5RLDM9YVhfQwHopptrAH0/R8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}