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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14cd4f68fe7b12b2048dc650ee2275daf02bf39739e125f488644033235c9429' 
  AND token = 'uEu7lIx7hHb5SH2BLRk6Ev7DIKw1MaQCORxrc98w9Z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}