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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c148fbc84bf9dd268a95c27ce282600399e38cbf14d5b5afacd6572e8d8f9102' 
  AND token = 'K20kzdgZD99OiwDcDzBoGhgMsb2lS3k7vYN/ec6ybD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}