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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a00a9a3d3d8a1a8758d8f6147e8762d80fce4001aa2a2f945bc40c882dc5e7e' 
  AND token = 'cO0lijFwUnaTKY9eq3Us2IjLoNVD7Qe5CiqyYEoJSAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}