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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87218754a7ad3ed69a4e3a0bd1f66f8bfc84d5965f2d6c7fffa50bb568b47520' 
  AND token = 'ShrsPEYRfHg6yvN/HXRNEHE509UibqH0hLOxlJmd8CE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}