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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8226c1374245612115567144b5f25ddb2eb64e7a7000d9c3b7055653abd7cb5f' 
  AND token = 'c9B0XbWJa88jyUNMeBIcmotYgZHuMRsjifVGOr+cgOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}