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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5401f7f986733bd8f39b29fd563a88db7d1d2d7664d7d7a10511c0dfea53f8ea' 
  AND token = 'syt6sFKQmTwhqX4mk5sDpLoSZ7d2rangPvLoxC+WFdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}