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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f0acb39760e8bf90b5b833c108c03a5aa2241369073f8a03c3cb891c7861b88' 
  AND token = 'xn/OFz4GCu7iKhRfTHSxRgBDwx2w3RTpV93jaF0efSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}