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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05e668b59d02ce57c551b2ea4aec425e20bedd9c26cff44cea53773cc4017023' 
  AND token = 'n8Ebpdeo/snPPk6tGKNJtBRwBT5L7DDtTQJ2c9z8AFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}