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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b8a7a1985de1374d865c35dd351ea62cd94ad9aa24347a54227f08c0e3b338c' 
  AND token = 'F0wt4wD56DIOL3CkRjPnivv/Iz5dX2tRBb1IR4zoo88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}