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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2205660e5ebdde6c532ec542335d3e18a45e97f9c57c2d7b12aa90c5e8705476' 
  AND token = 'I4hPgi7PVJ9AN31y4evVvSzsHnoTIfLS/VI16EqcziE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}