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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f02f2e167344e329945c2561ae8cda639dd4bd26f7d30946b601d33d4f504658' 
  AND token = 'mrAx6/egxx48i3r4H2+xrEyTRvW08pjwAOnzFiV7XjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}