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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73b7d2d18ac7a0611f36cd23b93a2e8ea18876cc868c325f07c6b67eafce96a0' 
  AND token = 'GxBmThGQDGDpMaSdN7oM9euHZW1b26uDTRx2eUtwTKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}