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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a5a43ed239edc75ae76661c266ae26c1d1d855ee727572904951dc12a484ac1' 
  AND token = '+3phs/gZ56K7bdXQxYqaq01vyrW5QpqJzxD9n4jwNjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}