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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4ff41ddd136e178d87af03f52acc2b57133af966478403150d0e9477643a6aa' 
  AND token = 'IiNZKAxwK7ZpLs8aEQVx0HVROSe/4eCDt0+Sqo1dx5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}