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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd10b8a3689daafd38fbb91f94ba6889740bec36ca712b7b10d91c49dfba5a66' 
  AND token = 'ub5f/TrHxrHU58EggCBj9Rp8ZPjE8MMm59uFbNtOr+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}