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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e50ea6628dfa33d5ba4fe12d2c42998ee42c5e11d8573de323de0bee76a213f0' 
  AND token = 'k2Xs1U1tFdoi1caHN5KyNp0cX0+ZWm6dxo8+XjJ321s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}