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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8c301121a20608ec89bc601820c953b1d0b744e8289072f7371e7db36e00ecb' 
  AND token = '/iYXJ7nAApzv1P20G1RtLzCf4XdfjiQRxmknuZgU210=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}