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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b7526ae9e99ff6fb56e78ee87c075e3627bdf78c0eafa20c3ba1676702ef96e' 
  AND token = 'OGr+HEMIjsddOX1Jv6Rhpo1RESbZ1zKet4ZFpSbYL2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}