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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f8020d395a5874594a03f7603200d67895885bc5db9f6913102dd776135265e' 
  AND token = 'UX67Z+wElzroTTcLO+cOeXPyT4IYxbGm+LHzBR6IkrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}