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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ad418d39acd4e5f8214f1aff9f17e37642f7f7df345ccc2b366b0a2fc12962b' 
  AND token = 'sy9VX5ROMzmX594s6dxbdv/MPp+020uXzDeyj3/tfsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}