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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55f0970a9919e1525098faec76b9b7ee3f0f2df9a1bea21711ca65bc62b6d787' 
  AND token = 'yz6pXHI0PT/NCEE0KE6sHzPsxLD1SIUKrmAMm8AWK/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}