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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e569a669d4c1224cb7065015b688a4b6445e9f6ce5ae97f27f9980c809f3f945' 
  AND token = 'dvpSmob5GJ1oEscJdNYhztoRfygb4izSttQWbFssKXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}