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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5dfce80b6b5cab0068a4a0a32d495f2d1151d10cb1dfcb83d7db00e984625eb' 
  AND token = 'tMCuRFvM2sFfsQQ9tYvrExHtjbwFJMcfdQPp+7AOQKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}