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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53b87f2ee1d7b83156a7faeda22d0cdf49e2b45815b66e0d16b4278cb8e95a56' 
  AND token = 'ALNjRs/Vl5tFIOpcqbZU8wVejxT1vtSMXtoD7TnslQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}