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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50ac1dcdfc2d8992696c5a3273d80ba6c913ff1d5ac7a3553a92a52050a25ce9' 
  AND token = 'p4pyX2Ofyb/84G+aefZ5YqLQnaP1wtOtZ6C9kgw74bU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}