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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8ac0e651ce12e224c3ed61b3285e31b512cc925607c326205d3a96076da009d' 
  AND token = '1G/pY4wiDnhD/UkM1B5RKULlr+sz5DZAZ5vogLFzn8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}