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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f210ae7f33df75dbb2da248e5a0395326081c6879789719ae5ba0d8a27e1cc64' 
  AND token = 'lDMVMUKWlwk6a3sjz4aGek9irez+PGA+4kgGxPzaMAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}