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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e781ef7fc5e75cc792fa96697e3e702c6c23c3b47d18f6dac299bc60a19a6be7' 
  AND token = 'HrqqljKfK+sAzbA0ojVGqznDwBr56Yi2NEtUZkq6wEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}