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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f189490fadd57bee279ae3e3826eab1376faed0b974333373b85649b9c3bc6d' 
  AND token = 'sukM0rdup3f+tkRTq28asd6DlFZWYkSRVRFlYmi5RmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}