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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd774a56e0de20f62bacf7e859cceaa2cb5bf45fcd6fb934058cb87b42a673b5a' 
  AND token = 'ryg4QuTJCuLMU2Klr9S0vIWgoCO7iyEAtIu5qrFudxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}