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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '418cf10b6d2a75dc6cf2060a4a1a186d87cef20bd9a00f86aade8bd1ed4740bb' 
  AND token = 'pq4T54JUPNSyyZKUc2bxvjqD22wFx9OC8dL0AY1cFgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}