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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0d6c4194fe215b55be2ddcd1cec1543ba7072a798150e7c620a198a62abf1c1' 
  AND token = 'IhFM0I/ApMVR6uZf36mmLD97as1cQRCI4cGhZRTiX/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}