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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cf1942d8c5e9c792abe0296e86b57ff4f15dbc55355778b75b831328041d85c' 
  AND token = 'GZa4BndpEBMaUBl7T9fGSQY2XMxgfjFFMk5WUZYRGM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}